Newsletter - July 2014   send this newsletter to a colleague
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Dear MDCT.net users,

Virtual colonoscopy (also called computed tomographic colonography, or CTC) is now a recommended radiological procedure for colon imaging. Since the early 1990s when it was developed, CTC technology has been finely improved, its capabilities have widely expanded, and its clinical indications have progressively evolved. Recent guidelines recognize CTC as the most acceptable, minimally invasive screening method for the detection of colorectal cancer and adenomatous polyps in both symptomatic and asymptomatic patients.
This month, MDCT.net publishes a comprehensive review of CTC’s recommended applications and contraindications in A. Laghi’s “Focus on”. Another contribution by the same author summarizes CTC’s safety profile, referring in particular to data from a meta-analysis that documents the low risk of colonic perforation. Three new clinical cases show the real-life use of CTC, and a selection of recently published research papers demonstrates the characteristics, benefits and risks of this examination in specific settings. Finally, the proposed e-book relates the history of CTC as both a colorectal imaging and screening modality and illustrates new directions in the practice of this advanced technique.

We remind you that suggestions for new topics to be covered in future issues are very appreciated: for this purpose please contact us at
editorial@mdct.net .

From the MDCT.net team
CT Colonography indications in 2014

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Bellini D, Rengo M, De Cecco CN, Iafrate F, Hassan C, Laghi A. Perforation rate in CT colonography: a systematic review of the literature and meta-analysis.
Eur Radiol. 2014 Jul;24(7):1487-96

Di Martino M, Saba L, Bosco S et al.  Hepatocellular carcinoma (HCC) in non-cirrhotic liver: clinical, radiological and pathological findings.
Eur Radiol. 2014 Jul;24(7):1446-1454

Plumb AA, Halligan S, Pendsé DA et al.  Sensitivity and specificity of CT colonography for the detection of colonic neoplasia after positive faecal occult blood testing: systematic review and meta-analysis
Eur Radiol. 2014 May;24(5):1049-1058

Flor N, Ceretti AP, Mezzanzanica M et al. Impact of contrast-enhanced computed tomography colonography on laparoscopic surgical planning of colorectal cancer.
Abdom Imaging. 2013 Oct;38(5):1024-1032

Flor N, Rigamonti P, Pisani Ceretti A et al.  Diverticular disease severity score based on CT colonography.
Eur Radiol. 2013 Oct;23(10):2723-2729

Perez-Johnston R, Hahn PF, Shenoy-Bhangle AS et al. Percutaneous biopsy of focal lesions of the gastrointestinal tract .
Abdom Imaging. 2013 Dec;38(6):1197-1202

Low rate of perforation during CT colonography
A. Laghi

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Abdominal pain and mild anemia
Man, 76 years old

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Rectal bleeding
Woman, 57 years old

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Gastrointestinal bleeding
Man, 88 years old

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Colorectal Cancer Screening and Computerized Tomographic Colonography
A Comprehensive Overview

Brooks D. Cash, ed.
Springer 2013
Table of Contents
Indications and Evidence for CTC
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