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The major role of CT in evaluating treatment response in HCC

Dear readers,

Hepatocellular carcinoma (HCC) response to treatment, including locoregional and molecular-targeted therapies, deserves strict post-procedural surveillance and a periodic follow-up in order to assess treatment effectiveness and plan subsequent patient management. New and more specific evaluation criteria have been introduced, which not only consider tumor burden and shrinkage but also estimate the decrease in viable tumor volume.

The major usefulness and high accuracy of CT in monitoring HCC treatment response are addressed in Dr. Anzidei’s Focus, which also highlights the fundamental contribution of this imaging technique in identifying procedure-related complications and the application of more advanced imaging parameters.

The e-book chapter selected for this Newsletter provides an in-depth demonstration of the use and advantages of imaging in the assessment of HCC treatment response, extending the considerations to other hepatobiliary and pancreatic malignancies. The successful utilization of CT in post-treatment follow-up of HCC is also illustrated in the new clinical case proposed herein.

Suggestions for topics to be covered in future issues of this newsletter are welcome as usual. Please send your ideas to us at

From the team