Biostatistics for Radiologists
Planning, Performing, and Writing a Radiologic Study
F. Sardanelli, G. Di Leo Springer 2010
Many radiological manuscripts are burdened by limitations relating to study design, definition
of enrollment criteria and standard of reference, lack of preliminary estimation of sample size,
and incorrect use of statistical tests. These limitations sometimes oblige the reviewer to
recommend rejection of a manuscript more frequently than would be the case if rejection were based
solely on inherent errors in technical performance or interpretation of imaging modalities.
An underlying aim of this book is to facilitate the interaction between radiologists and
statisticians by explaining the basics of statistical methods as applied to medical imaging. The
intention is to help develop a way of thinking beyond merely how to perform calculations and get p
values. Thus, radiologists will be able to solve small statistical problems and, more importantly,
to assume the right perspective during the crucial phase when a study is planned and undertaken.
Introduction - Diagnostic Performance - Variables and Measurement Scales, Normal Distribution, and Confidence Intervals - Null Hypothesis, Statistical Significance and Power - Non-Parametric Statistics - Linear Correlation and Regression - Reproducibility: Intraobserver and Interobserver Variability - Study Design, Systematic Reviews, and Levels of Evidence - Bias in Studies on Diagnostic Performance - How to Write a Radiologic Paper
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Introduction
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How to Write a Radiologic Paper
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Major Papers, Minor Papers, Invited Papers
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Which Medical Journal?
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Do We Always Need Institutional Review Board Approval and Informed
Consent?
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Title, Running Title and Title Page
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Four-section Scheme, Section Size and Editing Sequence
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«Introduction»: Why Did You Do It?
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«Materials and Methods»: What Did You Do and How Did You Do It?
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«Results»: What Did You Find?
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«Discussion»: What Is the Meaning of Your Findings?
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«References»
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«Abstract» and «Keywords»
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Shared Rules
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Other Recommendations
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Dealing with the Editor’s Response and the Reviewers’ Opinions
- To Conclude
